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Year Number of Results
2011 2
2012 1
2013 2
2014 5
2015 9
2016 9
2017 4
2019 2
2020 1
2022 1
2024 0

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29 results

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Page 1
Identification of essential genes for cancer immunotherapy.
Patel SJ, Sanjana NE, Kishton RJ, Eidizadeh A, Vodnala SK, Cam M, Gartner JJ, Jia L, Steinberg SM, Yamamoto TN, Merchant AS, Mehta GU, Chichura A, Shalem O, Tran E, Eil R, Sukumar M, Guijarro EP, Day CP, Robbins P, Feldman S, Merlino G, Zhang F, Restifo NP. Patel SJ, et al. Among authors: sukumar m. Nature. 2017 Aug 31;548(7669):537-542. doi: 10.1038/nature23477. Epub 2017 Aug 7. Nature. 2017. PMID: 28783722 Free PMC article.
T cell stemness and dysfunction in tumors are triggered by a common mechanism.
Vodnala SK, Eil R, Kishton RJ, Sukumar M, Yamamoto TN, Ha NH, Lee PH, Shin M, Patel SJ, Yu Z, Palmer DC, Kruhlak MJ, Liu X, Locasale JW, Huang J, Roychoudhuri R, Finkel T, Klebanoff CA, Restifo NP. Vodnala SK, et al. Among authors: sukumar m. Science. 2019 Mar 29;363(6434):eaau0135. doi: 10.1126/science.aau0135. Science. 2019. PMID: 30923193 Free PMC article.
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.
Sukumar M, Liu J, Ji Y, Subramanian M, Crompton JG, Yu Z, Roychoudhuri R, Palmer DC, Muranski P, Karoly ED, Mohney RP, Klebanoff CA, Lal A, Finkel T, Restifo NP, Gattinoni L. Sukumar M, et al. J Clin Invest. 2013 Oct;123(10):4479-88. doi: 10.1172/JCI69589. Epub 2013 Sep 16. J Clin Invest. 2013. PMID: 24091329 Free PMC article.
Ionic immune suppression within the tumour microenvironment limits T cell effector function.
Eil R, Vodnala SK, Clever D, Klebanoff CA, Sukumar M, Pan JH, Palmer DC, Gros A, Yamamoto TN, Patel SJ, Guittard GC, Yu Z, Carbonaro V, Okkenhaug K, Schrump DS, Linehan WM, Roychoudhuri R, Restifo NP. Eil R, et al. Among authors: sukumar m. Nature. 2016 Sep 22;537(7621):539-543. doi: 10.1038/nature19364. Epub 2016 Sep 14. Nature. 2016. PMID: 27626381 Free PMC article.
Metabolic reprograming of anti-tumor immunity.
Sukumar M, Kishton RJ, Restifo NP. Sukumar M, et al. Curr Opin Immunol. 2017 Jun;46:14-22. doi: 10.1016/j.coi.2017.03.011. Epub 2017 Apr 13. Curr Opin Immunol. 2017. PMID: 28412583 Free PMC article. Review.
Cancer genes disfavoring T cell immunity identified via integrated systems approach.
Kishton RJ, Patel SJ, Decker AE, Vodnala SK, Cam M, Yamamoto TN, Patel Y, Sukumar M, Yu Z, Ji M, Henning AN, Gurusamy D, Palmer DC, Stefanescu RA, Girvin AT, Lo W, Pasetto A, Malekzadeh P, Deniger DC, Wood KC, Sanjana NE, Restifo NP. Kishton RJ, et al. Among authors: sukumar m. Cell Rep. 2022 Aug 2;40(5):111153. doi: 10.1016/j.celrep.2022.111153. Cell Rep. 2022. PMID: 35926468 Free PMC article.
The transcription factor BACH2 promotes tumor immunosuppression.
Roychoudhuri R, Eil RL, Clever D, Klebanoff CA, Sukumar M, Grant FM, Yu Z, Mehta G, Liu H, Jin P, Ji Y, Palmer DC, Pan JH, Chichura A, Crompton JG, Patel SJ, Stroncek D, Wang E, Marincola FM, Okkenhaug K, Gattinoni L, Restifo NP. Roychoudhuri R, et al. Among authors: sukumar m. J Clin Invest. 2016 Feb;126(2):599-604. doi: 10.1172/JCI82884. Epub 2016 Jan 5. J Clin Invest. 2016. PMID: 26731475 Free PMC article.
Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.
Gurusamy D, Henning AN, Yamamoto TN, Yu Z, Zacharakis N, Krishna S, Kishton RJ, Vodnala SK, Eidizadeh A, Jia L, Kariya CM, Black MA, Eil R, Palmer DC, Pan JH, Sukumar M, Patel SJ, Restifo NP. Gurusamy D, et al. Among authors: sukumar m. Cancer Cell. 2020 Jun 8;37(6):818-833.e9. doi: 10.1016/j.ccell.2020.05.004. Cancer Cell. 2020. PMID: 32516591 Free PMC article.
29 results